منابع مشابه
Mitochondrial ribosomal proteins (MRPs) of yeast.
Mitochondrial ribosomal proteins (MRPs) are the counterparts in that organelle of the cytoplasmic ribosomal proteins in the host. Although the MRPs fulfil similar functions in protein biosynthesis, they are distinct in number, features and primary structures from the latter. Most progress in the eludication of the properties of individual MRPs, and in the characterization of the corresponding g...
متن کاملThe large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present.
Identification of all the protein components of the large subunit (39 S) of the mammalian mitochondrial ribosome has been achieved by carrying out proteolytic digestions of whole 39 S subunits followed by analysis of the resultant peptides by liquid chromatography and mass spectrometry. Peptide sequence information was used to search the human EST data bases and complete coding sequences were a...
متن کاملMammalian mitochondrial ribosomal proteins (4). Amino acid sequencing, characterization, and identification of corresponding gene sequences.
Mitochondrial ribosomal proteins (MRPs) are required for the translation of all 13 mitochondrial encoded genes in humans. It has been speculated that mutations and polymorphisms in the human MRPs may be a primary cause of some oxidative phosphorylation disorders or modulate the severity and tissue specificity of pathogenic mitochondrial DNA mutations. Although the sequences of most of the yeast...
متن کاملMammalian Mitochondrial Ribosomal Proteins (4) AMINO ACID SEQUENCING, CHARACTERIZATION, AND IDENTIFICATION OF CORRESPONDING
From the Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610-0245, Nemours Children’s Clinic, Jacksonville, Florida 32207, Ahmanson Department of Pediatrics, Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, California 90048-1865, Max-Delbrück-Center for Molecular Medicine, Robert-Rössle-Sraße 10, D-13125 Berlin, Germany, and I...
متن کاملMammalian mitochondrial ribosomal proteins (2). Amino acid sequencing, characterization, and identification of corresponding gene sequences.
Four different classes of mammalian mitochondrial ribosomal proteins were identified and characterized. Mature proteins were purified from bovine liver and subjected to N-terminal or matrix-assisted laser-desorption mass spectroscopic amino acid sequencing after tryptic in-gel digestion and high pressure liquid chromatography separation of the resulting peptides. Peptide sequences obtained were...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1998
ISSN: 0021-9258
DOI: 10.1074/jbc.273.52.34828